KPV 10mg vial
KPV is a 10mg lyophilized vial research peptide with 99.837% purity by HPLC (batch KP10-1221), supplied with a batch-matched COA, in stock and dispatched from the EU within 24 hours on working days.
- Content
- 10mg
- Purity
- 99.837%
- COA for this batch
- Included
Number of vials
Batch KP10-1221, tested 6 Jan 2026, 99.837% purity
Only 2 left in stock
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What is KPV?
Alpha-MSH-derived tripeptide studied in anti-inflammatory and gut research.
KPV is the C-terminal tripeptide (lysine-proline-valine) of alpha-melanocyte-stimulating hormone, studied for its anti-inflammatory signalling. It is studied in the context of NF-kB pathway modulation, pro-inflammatory cytokine regulation and intestinal-barrier integrity in cellular and preclinical models. Researchers investigate KPV for its role in mucosal-inflammation models and immune-signalling research. Its compact, stable structure makes it a reference compound in anti-inflammatory and gut-health research. Third-party tested to 99%+ purity and supplied as a lyophilized powder for laboratory reconstitution. For research purposes only, not for human consumption.
Specifications
- Purity
- 99.837%
- Physical Form
- Lyophilized powder
- Vial Size
- 10mg
- Storage
- -20°C
- Recommended Solvent
- Bacteriostatic water (0.9% benzyl alcohol)
- Reconstitution
- Add the solvent slowly along the inside wall of the vial and swirl gently; do not shake.
- Appearance
- White to off-white lyophilized powder
- Shelf Life
- 24 months unopened at -20°C
What does the COA for this batch show?
KPV
99.837% pureMeasured 10.86 mg vs labelled 10mg.
- Compound tested
- KPV
- Label
- 10mg
- Measured mass
- 10.86 mg
- Purity
- 99.837%
- Batch
- KP10-1221
- Test date
- 6 January 2026
Independent third-party analysis of the batch listed above. For research purposes only.
What is KPV studied for?
Studied in the context of
- KPV is the C-terminal tripeptide (lysine-proline-valine) of alpha-melanocyte-stimulating hormone, studied for its anti-inflammatory signalling.
- It is studied in the context of NF-kB pathway modulation, pro-inflammatory cytokine regulation and intestinal-barrier integrity in cellular and preclinical models.
- Researchers investigate KPV for its role in mucosal-inflammation models and immune-signalling research.
- Its compact, stable structure makes it a reference compound in anti-inflammatory and gut-health research.
How is KPV stored and handled?
Storage
Store lyophilized vials at -20°C, protected from light. Once reconstituted, refrigerate at 2-8°C and use within the recommended window.
Reconstitution
Use bacteriostatic water; add slowly down the inside wall of the vial. Swirl to dissolve, never shake. See the in-house peptide calculator for concentration (mg/ml) and syringe units (IU on a U-100 syringe).
For research use only
Not for human or veterinary consumption. Handle in accordance with your institution's laboratory safety protocols.
For research purposes only. Not for human consumption.
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Reviews cover packaging, delivery and documentation. Products are for laboratory research only; reviews contain no health or use claims.
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Before you order
Read before you order
All research guides- What is KPV? The alpha-MSH tripeptide in published researchKPV is the tripeptide Lys-Pro-Val, residues 11 to 13 at the C terminus of alpha-melanocyte stimulating hormone. In published research it reduced NF-kappaB signalling and inflammatory cytokine release in human intestinal, airway and immune cell lines, and it reduced signs of colitis in several mouse models. Its uptake into intestinal cells was linked to the PepT1 transporter. Studies also reported antimicrobial activity in vitro and faster corneal wound closure in rabbits. No controlled human trials have been published, so the evidence is cell and animal work. Vitality Peps supplies KPV for in vitro laboratory research only.8 min read
- KPV vs BPC-157: how the research comparesKPV is the tripeptide Lys-Pro-Val from the C terminus of alpha-MSH. BPC-157 is the pentadecapeptide GEPPPGKPADDAGLV, a partial sequence of a protein described in human gastric juice. In published research KPV reduced NF-kappaB signalling in human cell lines and reduced colitis in mice, with uptake linked to the PepT1 transporter. BPC-157 was associated with VEGFR2 signalling, tendon fibroblast migration and faster healing in rat injury models. Human data are minimal for both: none for KPV, two small uncontrolled reports for BPC-157. No study has tested them together. Both are supplied for in vitro research only.11 min read
- What is thymosin alpha 1? Thymalfasin in published researchThymosin alpha 1 is a heat stable, highly acidic peptide of 28 amino acids, isolated and sequenced from calf thymus in 1977 and produced in the body by cleavage of prothymosin alpha. Its synthetic form is called thymalfasin. In mouse and human cell studies it activated dendritic cells through Toll-like receptor signalling and induced the tolerance enzyme IDO. Human trials are numerous but mixed: an early sepsis trial reported a borderline result, while a 2025 placebo controlled phase 3 trial of 1,106 adults found no difference in 28 day mortality. Vitality Peps supplies it for in vitro laboratory research only.9 min read
- How to Store and Handle Research PeptidesLyophilised research peptides are stored in the refrigerator at 2 to 8 °C, or frozen at -20 °C for longer storage, sealed and protected from light. After reconstitution with [bacteriostatic water](/product/bacteriostatic-water-10ml) the solution is kept refrigerated, never shaken, and never refrozen.5 min read
- What your vial should look likeA sealed research peptide vial normally holds a white to off-white lyophilized cake or powder under an intact stopper and crimp cap. Pre-filled pens and nasal spray kits arrive sealed, with their documented appearance on the product page. Appearance never proves identity or purity; the COA for the batch does.4 min read
References and further reading
Published literature about this compound, listed for context only. Nothing here describes a use in humans.
- 1.Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo (pubmed.ncbi.nlm.nih.gov)
- 2.Terminal signal: anti-inflammatory effects of alpha-melanocyte-stimulating hormone related peptides beyond the pharmacophore (pubmed.ncbi.nlm.nih.gov)
- 3.Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease (pubmed.ncbi.nlm.nih.gov)
- 4.PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation (pubmed.ncbi.nlm.nih.gov)
- 5.Drug-loaded nanoparticles targeted to the colon with polysaccharide hydrogel reduce colitis in a mouse model (pubmed.ncbi.nlm.nih.gov)
- 6.Orally targeted delivery of tripeptide KPV via hyaluronic acid-functionalized nanoparticles efficiently alleviates ulcerative colitis (pubmed.ncbi.nlm.nih.gov)
1× KPV
€59.97